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Therapeutic hypothermia after cardiac arrest: monitoring hypothermia in intensive care units.

Last post 15 May 2010, 3:32 PM by Andrea Binks. 1 replies.
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  •  24 Apr 2010, 8:02 PM 489

    Therapeutic hypothermia after cardiac arrest: monitoring hypothermia in intensive care units.

    Binks and colleagues, in the second national survey on therapeutic hypothermia following cardiac arrest, demonstrated an impressive increase in levels of implementation of the International Liaison Committee on Resuscitation guidelines (from 28% to 85.6%) [1]. The survey has a very good response rate, thus reflecting practice across the country.

     

    One important aspect of practical implementation of therapeutic hypothermia remains unexplored. How many of the 208 intensive care units using therapeutic hypothermia post-cardiac arrest monitor ‘core temperature continuously’ during the cooling and rewarming period? The gold standard for true core temperature is the temperature of blood measured using a pulmonary artery catheter [2]. However, such invasive monitoring is rarely warranted, and core temperature is frequently measured at sites such as the oesophagus, nasopharynx, rectum, bladder and tympanic membrane, all of which have variable levels of accuracy. The oesophagus and nasopharynx offer more accurate estimates of core temperature than the  rectum and bladder, with tympanic membrane readings being the least accurate [3]. Temperature measurement at all these sites induces a time lag between registered and measured core temperature, which may lead to an overshoot of core temperature below the desired target temperature [3]. Intermittent temperature measurement via the tympanic membrane, and continuous temperature measurement via axillary probes remain popular choices of temperature monitoring in intensive care units, even when therapeutic hypothermia is being implemented. The survey by Binks did not assess methods of monitoring hypothermia. In view of the potential to induce inaccuracies, continuous core temperature monitoring via either a pulmonary artery catheter (if already in situ), or at one of the other sites (bladder, oesophagus, nasopharynx or rectum) is an integral part of therapeutic hypothermia after cardiac arrest [4].

     

    The failure to assess the methods of temperature monitoring issue is not a criticism of this survey, but I feel this should be incorporated into future studies or surveys on therapeutic hypothermia post-cardiac arrest.

     

    No external funding and no conflicts of interest declared

    V Sharma

    John Radcliffe Hospital

    Oxford, UK.

    E-mail: drvvs@rediffmail.com

     

    References

    1        Binks AC, Murphy RE, Prout RE, et al. Therapeutic hypothermia after cardiac arrest- implementation in UK intensive care units. Anaesthesia 2010; 65: 260-5.

    2        Akata T, Setoguchi H, Shirozu K, et al. Reliability of temperatures measured at standard monitoring sites as an index of brain temperature during deep hypothermic cardiopulmonary bypass conducted for thoracic aortic reconstruction. Journal of  Thoracic and Cardiovasccular Surgery 2007; 133: 1559-65.

    3        Polderman KH, Herold I. Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods. Critical Care Med 2009; 37: 1101-20.

    4        Nolan JP, Morley PT, Vanden Hoek TL, et al. Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation. Circulation 2003; 108: 118-21.

  •  15 May 2010, 3:32 PM 505 in reply to 489

    Re: Therapeutic hypothermia after cardiac arrest: monitoring hypothermia in intensive care units.

    We would like to thank Dr Sharma for his interest in our survey on therapeutic hypothermia [1]. We agree with him that it would have been interesting to ask about the method of temperature measurement, as some methods of temperature measurement have a long lag time or are inaccurate [2]. This may lead to an overshoot in temperature readings, particularly during the induction of hypothermia and in the rewarming phase.

     

    Our telephone survey was designed to be as brief as possible. We were mindful that clinicians were being asked to take time out of their duties on the intensive care unit to answer the survey questions, and are grateful for their generosity in participating.

     

    The authors of any future telephone surveys addressing this question need to give careful consideration to the potential benefits of each question asked, and weigh this against the burden imposed on the responders.

     

    A Binks

    A Padkin

    J Nolan

     

    Royal United Hospital, Bath

    E-mail: andrea.binks@nhs.net

     

     

    References 

      

    [1]       Binks A, Murphy RE, Prout RE, et al. Therapeutic hypothermia after cardiac arrest - implementation in UK intensive care units. Anaesthesia 2010; 65: 260-5.

    [2]       Polderman KH, Herold I. Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods. Critical Care Medicine 2009; 37:1101-20.

     

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